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This led to FDA black box warnings requiring screening for glucose intolerance before starting treatment and periodic monitoring during treatment, with recommendations against use in patients with poorly controlled diabetes

The rapidly evolving landscape for CKD-protective therapies in type 2 diabetes currently includes sodium-glucose cotransporter 2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP-1 RA), both of which demonstrate cardiorenal outcome benefits

Accutane is typically reserved for moderate to severe cases, particularly when other treatments have failed or when scarring or persistent skin problems are a concern

doi: 10.3390/medicines9090047

The surgical team gently split open the torn pectoral, creating a pocket to accommodate the cadaver tendon